This SEM photo of a hookworm’s head is so beautiful and vivid I thought I was looking at a digital painting. I want to frame this on the wall.
Hookworms are precious
I would call this “joyfully satisfied”.
Gaza today, September 1, 2014.
ICE, ICE, BABY For years, Death Valley presented visitors with a mystery: those of the famed “sliding rocks.” What made these small boulders seemingly glide across the playa, leaving tilled soil tracks in their wake? The answer appears in the scientific journal PLOS One: a layer of ice, and a push from the wind. Nature’s game of curling, we’d guess. (Photos [from top]: Richard Norris / Jim Norris / Michael Hartman via The New York Times)
WOW! 100 feet down! Only …..5300 more to go. Oh boy. This might take a while.
im following this blog where this person is trying to knit a mile long scarf this is amazing and deserves more attention
John Conway first theorized that it would be impossible to create a forever-expanding universe using these rules, which was proven wrong by a team at MIT, creating the “glider gun,” which is featured in the third gif.
Since then, thanks to computers, people all over the world have added new designs to the database, creating amazingly complex designs.
For example Andrew J. Wade created a design which replicates itself every 34 million generations! Furthermore it is also a spaceship (permanently moving pattern) and not only that, it was also the first spaceship that did not travel purely diagonally or horizontally/vertically! These types of spaceships are now appropriately named Knightships.
The simulation has some interesting properties, for example it has a theoretical maximum speed information can travel. Or simply, light speed - as that is the limit in our own universe. The limit is set to 1 cell per generation - after all how can you create something further than 1 cell away in one generation if you can only effect your immediate neighbours? And yet you can get things like the ‘stargate’ (Love the name, huge SG fan here.) which allows a space ship to travel 11 cells in just 6 generations.
Some smart people have even designed calculators, prime number generators and other incredibly complex patterns.
You can create your own patterns here: http://www.bitstorm.org/gameoflife/
All gifs were made from this video: https://www.youtube.com/watch?v=C2vgICfQawE
Within minutes after birth, every child in the U.S. undergoes a battery of tests designed to diagnose a host of conditions, including sickle cell disease. Thousands of children born in the developing world, however, aren’t so lucky, meaning many suffer and die from the disease each year.
A.J. Kumar hopes to put a halt to at least some of those deaths.
A Post-Doctoral Fellow in Chemistry and Chemical Biology working in the lab of George Whitesides, the Woodford L. and Ann A. Flowers University Professor, Kumar and colleagues, including other co-authors, have developed a new test for sickle cell disease that provides results in just 12 minutes and costs as little as 50 cents – far faster and cheaper than other tests. The test is described in a paper published this week in the Proceedings of the National Academy of Sciences.
"The tests we have today work great, they have a very high sensitivity," Kumar said. "But the equipment needed to run them costs in the tens of thousands of dollars, and they take hours to run. That’s not amenable to rural clinics, or even some cities where the medical infrastructure isn’t up to the standards we see in the U.S. That’s where having a rapid, low-cost test becomes important and this paper shows such a test can potentially work."
When run against more than 50 clinical samples – 26 positive and 26 negative – the new test showed good sensitivity and specificity for the disease, Kumar said, so the early evidence is promising, but additional testing will be needed to determine whether the test is truly accurate enough to use in the field.
The test designed by Kumar is deceptively simple, and works by connecting two ideas scientists have understood for decades.
The first is the notion that blood cells affected by the disease are denser than normal cells, and the second is that many polymers, when mixed in water, automatically separate into layers ordered by density.
Conventional methods to separate cells by density relied on layering liquids with different density by hand. The insight, arrived at by Charles Mace (now at Tufts) and Kumar, was that the self-forming layers could be used to separate cells, such as red blood cells, by density.
It wasn’t until a chance meeting with Dr. Thomas Stossel, however, that Kumar believed the technology might have a real impact on sickle cell disease.
"Initially, we started off working on malaria, because we thought when parasites invaded the cells, it would change their density," he said. "But when I met Tom Stossel on a panel at the Harvard Medical School, he said, ‘You need to work on sickle cell.’ He’s a hematologist by training and has been working with a non-profit in Zambia for the past decade, so he’s seen the need and the lack of a diagnostic tool."
When Kumar and colleagues ran tests with infected blood, their results were unmistakable. While healthy red blood cells settled in the tubes at specific levels, the dense cells from blood infected with sickle cell settled in a band significantly lower. The band of red cells could clearly be seen by eye.
Just showing that the test worked, however, wasn’t enough.
"We wanted to make the test as simple as possible," Kumar explained. "The idea was to make it something you could run from just a finger prick. Because these gradients assemble on their own, that meant we could make them in whatever volume we wanted, even a small capillary tube."
The design the team eventually settled on is barely larger than a toothpick. In the field, Kumar said, running the test is as simple as uncapping the tube, pricking a patient’s finger and allowing the blood to wick into the tube.
While further study is needed to determine how accurate and effective the test may be, Kumar said stopping even a few sickle-cell-related deaths would represent a victory.
"The best way to state it is in terms of the actual problem," he said. "About 300,000 children are born every year with sickle cell disease, and the vast majority – about 80 to 90 percent – are in either Africa or India, where for the most part, they aren’t going to get access to the current screening tests.
"There were studies recently that showed in sub-Saharan Africa, between 50 and 90 percent of the children born with sickle cell disease die before the age of 5,” he continued. “Whereas in the U.S. people don’t die from this disease as children, they can still live a full life. So my hope is that if this test is effective, it can make some small dent in those numbers.”
More information: Density-based separation in multiphase systems provides a simple method to identify sickle cell disease, PNAS, www.pnas.org/cgi/doi/10.1073/pnas.1414739111
Nikita Gill (London) Ghosts in the Woods, 2014
I say fuck all cops because, rather than be critical and take a stand against their fellow officers, good cops are nowhere to be fucking seen when wild shit goes down.
No police officer, especially police chief, gets on the news or social media or some type of fucking platform and says shit about bad cops.
So fuck them.
Fuck them for standing in camaraderie with corrupt individuals.
Post reblogged from with 1,163 notes
Video games don’t have to have good graphics to be good:
Video games don’t have to be about combat to be good:
Video games don’t have to have expansive dialogue and cutscenes to tell a good story:
Video games don’t have to be linear to envelop players in their worlds:
Video game bosses don’t have to be difficult to be fun:
Video games don’t have to lack color simply because they are “post-apocalyptic”:
Video Games can have lighthearted art design and still carry deeply dark themes:
Rethink video games.
reminder that they are up to something
River Structures Paul Hirzel
- River House I ‘The Bridge’ with 2,310sqf conditioned space is the living-guest quarters and it sets approx. 12 feet above grade. A 15-foot deep steel Howe truss system spans 80 feet at the center span with 32/16 foot balancing cantilevers at each end. The steel bridge truss supports a wood lattice that shades conditioned space below.
- River House II ‘The Lookout’ with 1,139sqf conditioned space is a multiuse space 1000 feet up river from the main structure. It is constructed with an inverted steel truss exoskeleton which cantilevers 40 feet over the river to view a rare Steelhead spawning pool below.
How did the moon form? The leading theory is that the Moon resulted from a glancing collision between the young Earth and an object the size of Mars. The above image series is based on several mathematical simulations of the Moon’s origin:
The Moon’s history begins with a collision between a young Earth (larger object) and a Mars-sized planet.
10 minutes: The now-molten mantle layers (gray) of the two planets are mixing together.
1 hour: The iron cores (orange) are melding together – Most of this iron will remain with Earth.
2 hours: Parts of the mantle are spinning off into a swarm of debris.
22 hours: Pieces of debris revolve around Earth, slowly gathering together.
1 week: The growing Moon’s gravity pulls in the remaining debris.
Page 1 of 659